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Radical rethinking on antioxidants

Antioxidant-rich products promise an easy way to stave off disease. Simply swallow two softgels daily or knock back a glass of goji-pomegranate juice and the “supercritical” compounds will neutralize those nasty free radicals that threaten your health.

Such bold claims seem logical. There’s evidence that free radicals, or oxidants, are involved in certain illnesses, including cancer and degenerative brain diseases.

And when oxidants turn up in our bodies — it happens when we turn food into energy or are exposed to infection, smoking and other triggers — we fight back by producing antioxidants that can soak them up like a sponge.

Thus a theory was born: Maybe oxidation and disease can be prevented by eating fortified foods or taking dietary supplements containing plant-based antioxidants, which include vitamins C and E, beta carotene and polyphenols (flavonoids).

But researchers now say antioxidants have been overhyped and widely misunderstood. Scientists haven’t determined how antioxidants work in our bodies; it’s also unclear whether dietary supplements have any beneficial effect. In some cases, studies suggest antioxidants may cause more harm than good.

One recent study found that antioxidant compounds caused fertility problems in mice. Though popular among athletes, antioxidants haven’t been shown to improve performance or speed recovery. To the contrary, supplementing with antioxidants may blunt the beneficial effects of working out. And while some dietary antioxidants may have a role in cancer prevention, excessive doses of some vitamins can aggravate illness or even cause it, researchers say.

“People should be aware that there is little to no data supporting the use of antioxidants to protect against disease,” said cardiologist Toren Finkel, chief of the Center for Molecular Medicine at the National Heart, Lung, and Blood Institute.

Yet “antioxidants” remains one of the hottest buzzwords in the health and wellness industry…..

LA Times: Read full article here