caramel colours

EFSA rules caramel colours are not carcinogenic or genotoxic

The European Food Safety Authority (EFSA) has concluded that caramel colours are not carcinogenic or genotoxic, and there is no evidence that they have adverse effects on human reproduction and child development.

The risk assessor is in the midst of a safety review for all food additives previously approved for use in the EU, as new science has been published since many were originally approved, in some cases as far back as the 1960s.

There are 4 variants of caramel colour in use: plain caramel (150a); caustic sulphite caramel (150b), ammonia caramel (150c) and sulphite ammonia caramel (150d). The group of colours is broadly used in food applications, including beer, brown bread, gravy browning, cola drinks, sauces, dressings and vinegar, whiskey, and confectionery.

EFSA has established a new group acceptable daily intake (ADI) level of 300 mg/kg bw/day for all four colours, based on their similar properties.

However for E150c it has set a more restrictive ADI of 100 mg/kg bw/day. This means that E150c can only contribute 100 mg/kg bw/day out of the 300 mg/kg bw/day total for all colours in the group.

The Joint WHO/FAO Expert Committee on Food Additives (JECFA) had previously established ADIs from 160mg/kg bw/d for E150b, E150c and E150d, but not for E150a.

US anti-caramel campaign

EFSA’s opinion comes on the heels of a new petition by US-based group Center for Science in the Public Interest (CSPI) for the Food and Drug Administration (FDA) to ban caramel colours.

The petition, filed in February, is based on the presence of 2-methylimidazole (2-MEI) and/or 4-MEI in the variants JECFA defines as class III (E150c) and class IV (E150d).

It cites government research that linked giving laboratory rats extremely high doses of 2-MEI and 4-MEI with increased risk of developing lung, liver, or thyroid cancer or leukemia.

CSPI executive director Michael Jacobson said: “Carcinogenic colorings have no place in the food supply, especially considering that their only function is a cosmetic one. The FDA should act quickly to revoke its approval of caramel colorings made with ammonia.”

The State of California has decided to include 4-MeI – formed naturally in most cooking, broiling, roasting and grilling — on its Proposition 65 list of possible carcinogens. As a result of this regulatory action, many soft drinks, soups, gravies, sauces and baked goods — foods produced using caramel color, a common ingredient produced by cooking sugar or corn syrup — would need to carry a warning label claiming that it is a possible carcinogen.

Industry associations such as the Grocery Manufacturers Association and the American Beverage Association have defended the use of these colours, noting that trace levels of 2-MEI and 4-MEI are ubiquitous in foods.

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Caramel Color is Safe and Harmless

Caramel color has undergone complete food safety testing more than 20 times in the past 35 years, and meets rigorous food safety standards around the world. There has never been a study that showed any health risk from caramel color. Read this statement by leading caramel colour supplier DD Williamson