New research backs Advantame’s safety

The high intensity sweetener Advantame is not associated with any adverse effects, according to a toxicology study over two generations of rats conducted by Ajinomoto. Advantame is a high intensity sweetener derived from the same amino acids as aspartame, and vanillin. While aspartame is around 200 times sweeter than sugar, Advantame is said to be “thousands of times” sweeter.

Results published in Food and Chemical Toxicology indicated that the no-observed-adverse-effect level (NOAEL) for reproductive and developmental toxicity was determined to be 50,000 ppm, which was equivalent to between 4 to 6 grams per kilogram of body weight per day.

The study, performed by Japan-based Ajinomoto scientists, reportedly adds to data from “several Good Laboratory Practices (GLP)-compliant toxicological studies, including those recommended by the FDA Redbook, and some human studies”.

Advantame’s intense sweetness means less would be required in formulations, although actual food sweetness levels would depend upon specific applications.

The Ajinomoto Company has filed petitions in countries such as the US, Australia and New Zealand to approve the sweetener.

In February of this year, approval moved a step closer in Australia and New Zealand, as the Food Standards Australia New Zealand (FSANZ) published its preferred option that the Food Standards Code be amended to approve the intense sweetener for sale and use…..

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